Abstract Cancer Hardware Glue stem-like cells (CSC) contribute to therapy resistance and recurrence.Focal adhesion kinase (FAK) has a role in CSC regulation.We determined the effect of FAK inhibition on breast CSC activity alone and in combination with adjuvant therapies.FAK inhibition reduced CSC activity and self-renewal across all molecular subt
BackgroundToxoplasma gondii is a zoonotic and foodborne intracellular parasite capable of inducing congenital infections, stillbirths and abortions in humans and animals, globally.The consumption of undercooked or raw mutton is "one of the vital risks" for acquiring toxoplasmosis: an asymptomatic condition in healthy persons, while life-threatening
Wheel Rear Epithelioid sarcoma (ES) is a rare malignant mesenchymal neoplasm that accounts for less than one percent of all soft-tissue sarcomas.Only two cases of ES involving the adrenal gland were found after a literature review.We report a case of an 82-year-old female initially presenting with right flank pain who was subsequently found to have
Financial fraud has extremely damaged the sustainable growth of financial markets as a serious problem worldwide.Nevertheless, it is fairly challenging to identify frauds with highly imbalanced dataset because ratio of non-fraud companies is very high compared to fraudulent ones.Intelligent financial statement fraud detection systems have therefore